CHAPTER 2: PHARMACOKINETICS AND PHARMACODYNAMICS
The force that binds or unites drug molecules is called:
The “lock-and-key” analogy represents:
A. The process of a drug binding to a receptor.
B. The affinity of a drug for a receptor.
C. The biological reaction produced by a drug receptor binding to a drug.
D. The inability of a drug to bind successfully to its specific receptor.
The potency of a drug refers to:
A. The maximal perceivable response to a specific dose.
B. The ability of a drug to exert its effects.
C. The difference between the doses of two drugs.
D. The amount of a drug needed to produce a pharmacological effect.
What is the therapeutic index of a drug with an ED50 of 50 and a TD50 of 125?
An individual is directed to take a total of 1.6 grams of ibuprofen in 4 equal increments throughout the day. Each tablet is 200 mg. Which of the following is the correct oral administration of the drug?
A. 2 tablets every 4 hours
B. 2 tablets every 6 hours
C. 6 tablets every 4 hours
D. 2 tablets every 2 hours
The duration of action of a drug is dependent on which of the following?
B. The rate of biotransformation
C. The length of time above the MEC
D. The health of the individual
Which of the following internal organs is initially responsible for metabolizing drug compounds?