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Chapter 3: Anti-inflammatory Medications

What is the role of eicosanoids in inflammation?

A. Arachidonic acid in the body is converted to which substance(s)?

B. What actions are prostaglandins responsible for in the various tissues of the body?

C. Which syndrome is attributed to a combination of aspirin and viral infection in children and young adults?

D. Acetaminophen produces what effects in the body?

E. What is the goal of the COX-2 inhibitors used in the inflammatory process?

F. Aspirin was derived from what product?

G. What is the most frequently reported complication of NSAIDs therapy?

H. The COX -2 inhibitors are targeted at which of the following?

I. Central nervous system/neurotransmitters

J. Blood-brain barrier

K. Inflammation from arthritis

L. Muscle spasms

With the recent advent of the use of over-the-counter NSAIDs for anti-inflammatory reasons, it is apparent that:

A. They are superior to aspirin in their action within the body.

B. There is no evidence that they are any better than aspirin in gaining a therapeutic effect on the system.

C. There is a high incidence of abuse with these drugs.

D. Acetaminophen is as good an anti-inflammatory without the side effects.

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