Pharmacologic: botanical agents
Treatment of external genital and perianal warts (Condylomata acuminata caused by human papillomavirus [HPV]) in immunocompetent patients 18 yr and older.
Beneficial effects may be due to antioxidant properties; made from extract of green tea. Therapeutic Effects: Regression of warts
Adverse Reactions/Side Effects
Local: burning, edema, erythema, induration, pain/discomfort, pruritus, erosion/ulceration, vesicular rash, bleeding, desquamation, discharge, irritation, phimosis, rash, regional lymphadenitis, scar.
PHYSICAL THERAPY IMPLICATIONS
Examination and Evaluation
Monitor any new or increased skin reactions at the site of application, including pain, inflammation, irritation, bleeding, burning, swelling, exfoliation, and rash. Report severe or prolonged skin reactions to the physician.
Absorption: Minimal systemic absorption (less than that of a cup of green tea).
Metabolism and Excretion: Unknown.
|ROUTE ||ONSET ||PEAK ||DURATION |
|topical ||unknown ||unknown ||unknown |
Contraindicated in: Not to be used for urethral, intra-vaginal, cervical, rectal, or intra-anal human papilloma viral disease or on open wounds.
Use Cautiously in: Safe and effective use in immunosuppressed patients has not been established; OB: Use during pregnancy only if potential maternal benefit justifies potential risk to the fetus; Pedi: Safe and effective use in patients <18 yr has not been established.
PO (Adults>18 yr): apply to warts tid for up to 16 wk.
15% Ointment: 15-g tubes.