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sertaconazole (ser-ta-kon-a-zole)
Ertaczo
Classification
Therapeutic: antifungals
Pharmacologic: imidazoles
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Topical treatment of interdigital tinea pedis in immunocompetent patients >12 yr.
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Inhibits synthesis of ergosterol, a component of fungal cell membrane, resulting in cytoplasmic leakage and fungal cell death. Therapeutic Effects: Resolution of fungal infection. Spectrum: Active against Trichophyton rubrum, T. mentagrophytes, Epidermophyton floccosum.
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Adverse Reactions/Side Effects
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Derm: application site reactions, burning, contact dermatitis, dry skin, tenderness.
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PHYSICAL THERAPY IMPLICATIONS
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Examination and Evaluation
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Avoid contact with cutaneous lesions when treating patient.
Always wash hands thoroughly and disinfect equipment (whirlpools, electrotherapeutic devices, treatment tables, and so forth) to help prevent the spread of infection.
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Patient/Client-Related Instruction
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Advise patient to report any increased local sensitivity to this drug (pain, burning, itching, swelling).
Instruct patient about proper hygiene; e.g., thoroughly wash and dry the affected area, wear clean socks and ventilated shoes for tinea pedis, and so forth.
Advise patient to apply the drug as directed for the full course of treatment even if feeling better.
Inform patient that full therapeutic response may take up to 4 wk.
Advise patient to seek medical help if infections persist or recur after the full treatment. Recurrent fungal infections may be a sign of systemic illness.
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Absorption: Minimal systemic absorption.
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Metabolism and Excretion: Unknown.
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Contraindications/Precautions
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Contraindicated in: Hypersensitivity to sertaconazole or other imidazoles.
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Use Cautiously in: Children <12 yr, lactation (safety not established); Pregnancy (use only if clearly needed).
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Topical (Adults and Children >12 yr): Apply bid for 4 wk.
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2% cream: 15-g tube, 30-g tube.