Therapeutic: antivirals (topical)
Treatment of recurrent oral-facial herpes simplex (cold sores, fever blisters).
Prevents herpes simplex virus from entering cells by preventing viral particles from fusing with cell membranes. Therapeutic Effects: Reduced healing time. Decreased duration of symptoms (pain, burning, itching, tingling).
Adverse Reactions/Side Effects
All local reactions occurred at site of application Local: acne, skin, itching, rash.
PHYSICAL THERAPY IMPLICATIONS
Examination and Evaluation
Avoid contact with cutaneous or mucosal lesions when treating patient.
Always wash hands thoroughly and disinfect equipment (whirlpools, electrotherapeutic devices, treatment tables, and so forth) to help prevent the spread of infection. Use universal precautions as indicated for specific patients.
Advise patient to apply medication as directed. Docosanol should not be used more frequently or longer than prescribed.
Remind patient that docosanol does not cure herpes infections. The virus lies dormant in nerve cells, and this drug will not prevent the spread of infection to others.
Metabolism and Excretion: Unknown.
Contraindicated in: Hypersensitivity to docosanol or any other components of the formulation (benzyl alcohol, mineral oil, propylene glycol, or sucrose).
Use Cautiously in: Children <12 yr (safety not established); Pregnancy (use only if clearly needed).
Drug-Drug: None significant.
Topical (Adults and Children ≥12 yr): Apply small amount 5 times daily to sores on lips or face until healed.
Cream: 10% cream in 2-g tubes OTC.