difluprednate (ophthalmic) (dye-floo-pred-nate)
Therapeutic: ocular agents
Treatment of inflammation and pain associated with ocular surgery.
Decreases inflammation. Therapeutic Effects: Decreased pain and inflammation following ocular surgery.
Adverse Reactions/Side Effects
(CAPITALS indicate life-threatening; underlines indicate most frequent.) EENT: ↑ intraocular pressure, blepharitis, cataracts, conjunctival hyperemia, corneal edema, delayed healing, eye pain, infections, iritis, photophobia.
PHYSICAL THERAPY IMPLICATIONS
Examination and Evaluation
Assess the eye to help document whether drug therapy is successful in resolving ocular pain and inflammation.
Monitor any new or increased reactions at the site of application such as pain, infection, swelling, redness, cloudy/blurry vision, and increased sensitivity to light (photophobia). Report increased ocular reactions to the physician.
Absorption: Limited systemic absorption.
Metabolism and Excretion: Unknown.
|ROUTE ||ONSET ||PEAK ||DURATION |
|Ophth ||unknown ||unknown ||unknown |
Contraindicated in: Active viral, mycobacterial or fungal infection of eyes and surrounding structures.
Use Cautiously in: OB: Use in pregnancy only if potential benefit justifies potential risk to the fetus; Lactation: Use cautiously during lactation; Pedi: Safety and effectiveness in children have not been established.
Ophth (Adults): 1 drop four times daily, starting 24 hr after surgery for 2 wk, then twice daily for 1 week, then further tapered based on response.
Ophthalmic emulsion: 0.05% in 5 mL bottle.